Central Autonomic Dysfunction Delays Recovery of Fingolimod Induced Heart Rate Slowing

Central Autonomic Dysfunction Delays Recovery of Fingolimod Induced Heart Rate Slowing

BACKGROUND In multiple sclerosis (MS) patients, Fingolimod may induce prolonged heart-rate slowing which might be caused by MS-related central autonomic lesions. OBJECTIVES To evaluate whether MS-patients with prolonged heart-rate slowing (> six hours) upon Fingolimod show cardiovascular-autonomic dysfunction before Fingolimod-initiation. METHODS Before Fingolimod-initiation, we recorded el...

Erectile dysfunction and heart rate recovery. Is it autonomic nervous system?

Heart Rate Variability for Quantification of Autonomic Dysfunction in Fibromyalgia.

OBJECTIVE To quantify autonomic dysfunction in fibromyalgia patients compared to healthy controls using heart rate variability (HRV). METHODS Sixteen patients with fibromyalgia and 16 healthy controls were recruited in this case control study. HRV was measured using the time-domain method incorporating the following parameters: total heartbeats, the mean of intervals between consecutive heart...

Autonomic Dysfunction and Risk Stratification Assessed from Heart Rate Pattern

The modulation of the autonomic nervous system (ANS) under physiological and pathophysiological conditions is in focus of recent research. Many patients with cardio- and cerebrovascular diseases display features of sympathovagal dysregulation. Measuring specific ANS parameters could improve risk stratification. Thus, the early diagnosis of ANS dysfunction in these patients poses a great challen...

Heart Rate Variability, Heart Rate Recovery, and Heart Rate Turbulence Represent Different Components of the Cardiac Autonomic Nervous System